Michele,
To answer your question simply, no, in the reflowable ebook formats, they cannot because the content is not and cannot be set to a fixed page size like a PDF. That’s kind of the nature of reflowable ebooks, and with so many different ereaders and apps on the market there really is no way to control the literal “page size” in the reflowable books that we see in print because everyone wants their device to be unique and each one has a different screen size. Ereaders also dont really have literal “pages” as we think of them in print (unless you do the fixed layout format, which, unless your book is a textbook, you shouldnt use), you kind of have to think of each chapter of your book as one long block of content, similar to how you would see an article on a web page (and if you resize the window it will reflow the content), ereaders populate the screen with as much content as it can and when you resize the text it just adjusts what content is on the screen. A good example of this, if you have an iPad, is to set iBooks to Scroll mode.
Hope that was helpful,
Aaron
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