Thanks to you both! I definitely understand about the lossy quality of jpegs (I’m from the old CMYK tiffs school). But part of the problem we were encountering was images being automatically converted from tiff to gif by our vendor for our full-text versions (who converts from collected InDesign output); they use jpegs untouched. We only save the images (which are usually author-supplied jpegs) one time; we’ll test to be sure, but I think we’ll be ok. And on the RGB front, my printer has already sent color profiles to convert to CMYK when exporting to PDF. It’s a new world, but I’m adapting! Thanks again.

Mind blown. (Thank you!)

Thanks. I’m working on new templates (based on all the good stuff I learned at the conference in DC!), and layers will be a part of them. But I don’t think layers will help with this specific issue, unless I can turn them off at the book level? We publish individual articles (online ahead of print) on a weekly basis; each of those articles is it’s own separate InDesign file. Then articles from various weeks are bundled together in a book for the print issues, and that’s where the running head comes in — we have it as a nonprinting item on our master pages until we make the print issues. The header text is J Neurosurg Spine ##:A–1, 2016, with the ## being a placeholder for the volume number, the A being the first page number of the article, and the 1 being the last page (text variables). We’ve tried doing a find/replace on that whole header with the idea being that I can just change the ## and the 2016 and leave everything else the same. But, when I copy and paste that line into the Find and Change to fields, it becomes J Neurosurg Spine ##:\x{0018}–\x{0018}, 2016, and the result is that my page range goes from being first to last to being first to first (i.e., if I apply a change, it becomes J Neurosurg Spine ##:A–A, 2016). And I don’t see a way to reinsert the last page number into the search field. If there were a way to maintain the variable page numbers during the search, that would be an easy fix. But I think I’d have to hide layers in each individual article in order to search layers only? (Depending on the journal, there can be 20-40 articles in a book.) Thanks again for your help.