Reply To: interactive .pdfs and Epubs

You are getting some bad information. The problem of a book with that many images is that it’s likely going to have to be very expensive to cover the cost of the download penalty.
First, typical reflowable epubs aren’t suited to image-heavy books (I have 2 for sale but they had to be completely reformatted to include only 1 image per page). You can sell non-reflowable ebooks on Amazon by using the Textbook Creator (this requires a pdf, the result is essentially a fixed-layout epub). Of this type I have one title up and a second (1600+ images) soon to go. I haven’t explored all the outlets but most of the others will deal with fixed-layout epubs, just not pdfs. I’ve never tried to split a single fixed-layout epub or interactive pdf into sections with non-consecutive numbering but I can’t see a theoretical bar. The pages may be numbered starting with 1 in the pdf, but page numbers from the indesign master pages should be retained. Mostly I foresee a horrible problem with indices.