Reply To: Ruler Guides on Master Pages

Yes they do, place a guide on a master page that is applied to the page in the document.

Can you drag guides onto the page you are having problems with? Does this happen wiht all documents or only one?
If it is only one then it might be corrupt.
To fix that corruption save the file as an IDML file and then reopen, If this solves the problem you have a corrupt document.

If you want to reset the preferences read this link you can save a copy of your shortcuts and then replace them after you reset preferences.
https://helpx.adobe.com/indesign/using/customize-menus-keyboard-shortcuts.html