Reply To: Image degradation on resaving from PSD to JPEG

I think i will make myself clear. I frequently get digital images which are too large (pixel-size). Hence, I need to crop, retouch the images & reduce the image size in Photoshop before placing in Indesign. I save the image as JPEG & place it in an Indesign document. Now sometimes the same image is to be reused, but its size needs to be further reduced according to the format. What I want to know is that should I first save the retouched image as PSD, so that while placing multiple times in Indesign in varying sizes, I can do a Save As in JPEG form the second or third time or should I use the original every time, do the changes in Photoshop, get the final size & save as JPEG. Would saving as PSD after making changes to the original image in Photoshop the first time & then later on saving as JPEG the second time cause image degradation.